The role of epigenetics in the biology of multiple myeloma

  title={The role of epigenetics in the biology of multiple myeloma},
  author={K. P. Dimopoulos and Peter Gimsing and Kirsten Gr\onb{\ae}k},
  booktitle={Blood cancer journal},
Several recent studies have highlighted the biological complexity of multiple myeloma (MM) that arises as a result of several disrupted cancer pathways. Apart from the central role of genetic abnormalities, epigenetic aberrations have also been shown to be important players in the development of MM, and a lot of research during the past decades has focused on the ways DNA methylation, histone modifications and noncoding RNAs contribute to the pathobiology of MM. This has led to, apart from… CONTINUE READING
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