The role of epigenetic dysregulation in the epidemic of allergic disease

  title={The role of epigenetic dysregulation in the epidemic of allergic disease},
  author={Susan L. Prescott and Richard Saffery},
  booktitle={Clinical Epigenetics},
The epidemic of allergic disease in early life is one of the clearest indicators that the developing immune system is vulnerable to modern environmental changes. A range of environmental exposures epidemiologically associated with allergic disease have been shown to have effects on the foetal immune function in pregnancy, including microbial burden, dietary changes and environmental pollutants. Preliminary studies now suggest that these early effects on immune development may be mediated… CONTINUE READING
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