The role of endogenous prostaglandin E in angiotensin-II-induced drinking in rats.


Oral administration of indomethacin, a nonsteroidal anti-inflammatory agent which suppresses endogenous prostaglandin E2 (PGE2) levels in plasma, results in an augmentation of total water intake and a shortening of the latency to drink in response to an intravenous infusion of angiotensin II. This same treatment has no effect on water intake stimulated by… (More)


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