The role of endogenous opiates in LH secretion during the menstrual cycle.

@article{Quigley1980TheRO,
  title={The role of endogenous opiates in LH secretion during the menstrual cycle.},
  author={Michelle E Quigley and Samuel Yen},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1980},
  volume={51 1},
  pages={179-81}
}
To determine whether endogenous opiates exert an inhibitory action on LH secretion during the menstrual cycle, LH increments were examined in response to a specific opiate antagonist, naloxone, infused at 1.6 mg/hr for 4 hrs. Naloxone had no discernible effect on LH release during the early follicular phase. By contrast, a significant LH increment was observed in both the late follicular and mid-luteal phases of the cycle but the patterns of LH increment were distinct. Late follicular subjects… CONTINUE READING