The role of dorsal raphe nucleus serotonergic and non-serotonergic neurons, and of their receptors, in regulating waking and rapid eye movement (REM) sleep.

@article{Monti2010TheRO,
  title={The role of dorsal raphe nucleus serotonergic and non-serotonergic neurons, and of their receptors, in regulating waking and rapid eye movement (REM) sleep.},
  author={Jaime M. Monti},
  journal={Sleep medicine reviews},
  year={2010},
  volume={14 5},
  pages={
          319-27
        }
}
  • J. Monti
  • Published 1 October 2010
  • Biology
  • Sleep medicine reviews

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It is proposed that the DOI activation of long-projection GABAergic neurons that express 5-HT2A/2C receptors would be responsible for the inhibition of cholinergic cells in the laterodorsal tegmental and pedunculopontine te segmental nuclei (LDT/PPT) and the suppression of REMS.
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Analysis of spontaneous (sEPSCs) and evoked (eEPSC) synaptic events led to the conclusion that nAChRs were located at the postsynaptic membrane.
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