The role of dopaminergic transmission through D1-like and D2-like receptors in amphetamine-induced rat ultrasonic vocalizations

@article{Wright2012TheRO,
  title={The role of dopaminergic transmission through D1-like and D2-like receptors in amphetamine-induced rat ultrasonic vocalizations},
  author={J. Wright and May Dobosiewicz and P. Clarke},
  journal={Psychopharmacology},
  year={2012},
  volume={225},
  pages={853-868}
}
  • J. Wright, May Dobosiewicz, P. Clarke
  • Published 2012
  • Chemistry, Medicine
  • Psychopharmacology
  • RationaleSystemic amphetamine (AMPH) administration increases the rate of 50-kHz ultrasonic vocalizations (USVs) in adult rats and preferentially enhances the ‘trill’ subtype; these effects of AMPH critically depend on noradrenergic transmission, but the possible contributions of dopamine are unclear.ObjectiveTo assess the role of dopamine in 50-kHz USVs emitted drug-free and following systemic AMPH administration.MethodsAdult male Long–Evans rats pre-selected for high AMPH-induced calling… CONTINUE READING
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