The role of dietary n-6 fatty acids in the prevention of cardiovascular disease

  title={The role of dietary n-6 fatty acids in the prevention of cardiovascular disease},
  author={Walter C. Willett},
  journal={Journal of Cardiovascular Medicine},
  • W. Willett
  • Published 1 September 2007
  • Medicine
  • Journal of Cardiovascular Medicine
n-6 Fatty acids, like n-3 fatty acids, play essential roles in many biological functions. Because n-6 fatty acids are the precursors of proinflammatory eicosanoids, higher intakes have been suggested to be detrimental, and the ratio of n-6 to n-3 fatty acids has been suggested by some to be particularly important. However, this hypothesis is based on minimal evidence, and in humans higher intakes of n-6 fatty acids have not been associated with elevated levels of inflammatory markers. n-6 Fatty… 

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