The role of desmin and N-cadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells.

@article{Davidson2001TheRO,
  title={The role of desmin and N-cadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells.},
  author={Ben Davidson and S\oren Nielsen and Jette Christensen and Pia Asschenfeldt and Aasmund Berner and Bj\orn Risberg and Preben Johansen},
  journal={The American journal of surgical pathology},
  year={2001},
  volume={25 11},
  pages={1405-12}
}
The objective of the present study was to analyze the role of the mesothelial markers desmin and N-cadherin in the diagnostic panel of serous effusions. A total of 181 pleural and peritoneal effusions consisted of 101 cases cytologically diagnosed as malignant (89 carcinomas, 12 mesotheliomas), 78 benign, and 2 inconclusive specimens. All specimens were immunostained using 11 antibodies, against epithelial membrane antigen, Ber-EP4, carcinoembryonic antigen, E-cadherin, CA 125, N-cadherin… CONTINUE READING
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