The role of dendritic and epithelial cells as master regulators of allergic airway inflammation.

@article{Lambrecht2010TheRO,
  title={The role of dendritic and epithelial cells as master regulators of allergic airway inflammation.},
  author={Bart M. Lambrecht and Hamida Hammad},
  journal={Lancet},
  year={2010},
  volume={376 9743},
  pages={835-43}
}
Lung dendritic cells bridge innate and adaptive immunity, integrating a variety of stimuli from allergens, microbial colonisation, environmental pollution, and innate immune cells into a signal for T lymphocytes of the adaptive immune system. Dendritic cells have a pivotal role in the activation of T helper (Th) 2 cells and allergic inflammation. Lung dendritic cells can also prevent harmful immune responses to innocuous inhaled antigens via induction of regulatory T cells or Th1 cells. In our… CONTINUE READING