• Biology, Chemistry, Medicine
  • Published in The Journal of physiology 2017
  • DOI:10.1113/JP275072

The role of declining adaptive homeostasis in ageing

@article{Pomatto2017TheRO,
  title={The role of declining adaptive homeostasis in ageing},
  author={Laura C. D. Pomatto and Kelvin J A Davies},
  journal={The Journal of Physiology},
  year={2017},
  volume={595},
  pages={7275–7309}
}
Adaptive homeostasis is "the transient expansion or contraction of the homeostatic range for any given physiological parameter in response to exposure to sub-toxic, non-damaging, signalling molecules or events, or the removal or cessation of such molecules or events" (Davies, 2016). Adaptive homeostasis enables biological systems to make continuous short-term adjustments for optimal functioning despite ever-changing internal and external environments. Initiation of adaptation in response to an… CONTINUE READING
15
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

Adaptive homeostasis and the free radical theory of ageing

VIEW 17 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 388 REFERENCES

Adaptive homeostasis

  • KJA Davies
  • Mol Aspects Med 49, 1–7.
  • 2016
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Tensional homeostasis and the malignant phenotype.

VIEW 23 EXCERPTS
HIGHLY INFLUENTIAL

Sudden cardiac death triggered by an earthquake.

VIEW 22 EXCERPTS
HIGHLY INFLUENTIAL

Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress.

VIEW 22 EXCERPTS
HIGHLY INFLUENTIAL