The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening.

  title={The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening.},
  author={Irving Elliot Salit and Alice Lytwyn and Janet M. Raboud and Marie Sano and Sylvia Chong and Christina C Diong and William Chapman and James B. Mahony and Jill Tinmouth},
  volume={24 9},
OBJECTIVE To assess anal oncogenic human papillomavirus (HPV) and anal cytology as screening tests for detecting high-grade anal intraepithelial neoplasia (AIN 2+), as this is an immediate anal cancer precursor. DESIGN Cross-sectional study of 401 HIV-positive men who have sex with men (MSM). The endpoint was histologically confirmed AIN 2+ obtained by high-resolution anoscopy. Cytology and biopsy specimens were assigned random numbers and independently assessed by two pathologists. METHODS… CONTINUE READING
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