The role of cytokines in infection-related behavior.

  title={The role of cytokines in infection-related behavior.},
  author={Adrian J. Dunn and Artur H. Swiergiel},
  journal={Annals of the New York Academy of Sciences},
Infections are associated with a specific behavioral pattern that includes hypomotility, hypophagia, increased sleep, decreased libido, and decreased exploration. This behavioral response is considered adaptive and important for the survival of the animal. A similar behavioral pattern was observed following treatment with endotoxin (lipopolysaccharide [LPS]) and cytokines, such as interleukin-1 (IL-1). Because the secretion of these cytokines is induced by LPS and infections, it is possible… CONTINUE READING


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