The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells.

@article{Barata2004TheRO,
  title={The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells.},
  author={Hosana Barata and Michael Thompson and Weronika Zielinska and Young Soo Han and Carlos B. Mantilla and Yedatore S Prakash and Simone S Feitoza and Gary C. Sieck and Eduardo Nunes Chini},
  journal={Endocrinology},
  year={2004},
  volume={145 2},
  pages={881-9}
}
Human myometrial contraction plays a fundamental role in labor. Dysfunction of uterine contraction is an important cause of labor progression failure. Although the mechanisms controlling uterine contraction are not completely understood, intracellular Ca2+ mobilization plays an important role during uterine contraction. Several mechanisms of intracellular Ca2+ mobilization are present in smooth muscle, but in the human uterus, only 1,4,5-trisphosphate-induced Ca2+ release has been studied… CONTINUE READING