• Corpus ID: 29927088

The role of cosmeceuticals in antiaging therapy.

  title={The role of cosmeceuticals in antiaging therapy.},
  author={Jason K. Rivers},
  journal={Skin therapy letter},
  volume={13 8},
  • J. Rivers
  • Published 1 November 2008
  • Medicine
  • Skin therapy letter
As baby boomers get older, they have shown an increasing interest in maintaining a youthful appearance. As a result, there has been a corresponding increase in topical antiaging formulations, which are commonly referred to as cosmeceuticals. These products come with a seemingly limitless number of key active ingredients and claims of reducing the signs of aging and/or maintaining a youthful appearance. This paper reviews the more common cosmeceutical ingredients. 

Gold for Facial Skin Care: Fact or Fiction?

It is believed that anti-aging preparations or cosmeceuticals, as less-invasive, nonsurgical alternatives, can retard the aging effect of the skin, but the therapeutic benefits of most products remain unsubstantiated.

Relevant Topical Skin Care Products for Prevention and Treatment of Aging Skin.

  • Sarmela Sunder
  • Medicine
    Facial plastic surgery clinics of North America
  • 2019

Liposomes in cosmeceutics

This review deals with the potential of liposomes as a skin delivery system for cosmeceuticals, with a focus on the clinical application ofliposomes.

Current Cosmetic Treatments in Pregnancy

The goal of this work is to report the main dermatological alterations occurring during pregnancy and actual cosmetic protocols available and recommended for safe use, according to the current legislation.

An antiaging skin care system containing alpha hydroxy acids and vitamins improves the biomechanical parameters of facial skin

An antiaging skin care system containing AHAs and vitamins significantly improves the biomechanical parameters of the skin including wrinkles and skin texture, as well as elasticity without significant adverse effects.

An Innovative Concept Gel to Prevent Skin Aging

Thirty-three subjects completed the study showing, after only 20 minutes from the 1st product application, a clinically important and statistically significant improvement of crow’s feet, skin dullness clinical score and cutaneous microrelief clinical score.

Kojic acid applications in cosmetic and pharmaceutical preparations.

Commentary: Revisiting the Data: Mild Resting Glabellar Lines Improve With OnabotulinumtoxinA

  • M. E. ContrerasJoel L Cohen
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2010
Dr. Cohen has served as a consultant and clinical trial participant for Allergan, Medicis and Merz and has no conflicts.

The quest for a whiter shade of pale in skin care

The quest for a whiter shade of pale dates back to ancient civilizations, when a pale complexion was associated with aristocratic lineage. During the Tang dynasty (618-907), Chinese women used ground



Insight into skin lightening cosmeceuticals for women of color.

Common over-the-counter agents addressing their advantages and disadvantages will often be the most effective treatment available.

Interaction of vitamins C and E as better cosmeceuticals

  • K. Burke
  • Chemistry
    Dermatologic therapy
  • 2007
Although many cosmeceutical formulations contain vitamin C and/or vitamin E, very few are actually effective in topical application because the form of the molecule is not absorbed or metabolized effectively by the skin.

Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin 1

Niacinamide was well tolerated by the skin and provided significant improvements versus control in end points evaluated previously: fine lines/wrinkles, hyperpigmentation spots, texture, and red blotchiness.

Review of skin-lightening agents.

  • M. RendonJ. Gaviria
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2005
The speed of efficacy and type and extent of side effects vary greatly among depigmenting agents, and knowing the properties associated with each agent enables a physician to choose a product that will best meet a patient's expectations and minimize adverse reactions.

Tensile properties and contours of aging facial skin. A controlled double‐blind comparative study of the effects of retinol, melibiose‐lactose and their association

  • C. Piérard‐franchimontD. Castelli G. Piérard
  • Medicine
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging
  • 1998
This instrumentally assessed and compared the effect of either 0.04% retinol, 1% melibiose and 4% lactose and their association (ROL‐ME‐L) to increase the firmness and smoothness of facial skin.


The author uses kinetin, a plant-derived nucleotide, as an example to summarize the approach to advising a patient on a new product, and examines whether the molecule is able to penetrate the stratum corneum and if it may be useful as a photoprotectant.

Niacinamide: A B vitamin that improves aging facial skin appearance.

  • D. BissettJ. OblongC. Berge
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2005
Results revealed a variety of significant skin appearance improvement effects for topical niacinamide: reductions in fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness (yellowing).

Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety

N nanoparticles have shown a good potential in improving the stability, tolerability and efficacy of retinoid like tretinoin and retinol, however, more elaborate clinical studies are required to confirm their advantage in the delivery of topical retinoids.

Retinoids in cosmeceuticals

Retinaldehyde, which is fairly well tolerated, seems to be the most efficient cosmeceutical retinoid; it has significant efficiency toward oxidative stress, cutaneous bacterial flora, epidermis renewing, and photoaging.

Improvement of naturally aged skin with vitamin A (retinol).

With greater skin matrix synthesis, retinol-treated aged skin is more likely to withstand skin injury and ulcer formation along with improved appearance, and significant induction of glycosaminoglycan and increased collagen production are most likely responsible for wrinkle effacement.