The role of corepressors in transcriptional regulation by nuclear hormone receptors.

@article{Privalsky2004TheRO,
  title={The role of corepressors in transcriptional regulation by nuclear hormone receptors.},
  author={Martin L. Privalsky},
  journal={Annual review of physiology},
  year={2004},
  volume={66},
  pages={315-60}
}
Nuclear receptors (also known as nuclear hormone receptors) are hormone-regulated transcription factors that control many important physiological and developmental processes in animals and humans. Defects in receptor function result in disease. The diverse biological roles of these receptors reflect their surprisingly versatile transcriptional properties, with many receptors possessing the ability to both repress and activate target gene expression. These bipolar transcriptional properties are… CONTINUE READING
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