The role of colonic metabolism in lactose intolerance.

  title={The role of colonic metabolism in lactose intolerance.},
  author={Tao He and Koen Venema and Marion G. Priebe and Gjalt W. Welling and R -J M Brummer and Roel J Vonk},
  journal={European journal of clinical investigation},
  volume={38 8},
Lactose maldigestion and intolerance affect a large part of the world population. The underlying factors of lactose intolerance are not fully understood. In this review, the role of colonic metabolism is discussed, i.e. fermentation of lactose by the colonic microbiota, colonic processing of the fermentation metabolites and how these processes would play a role in the pathophysiology of lactose intolerance. We suggest that the balance between the removal and production rate of osmotic-active… CONTINUE READING


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