The role of clathrin-coated vesicles in acrosome formation.

  title={The role of clathrin-coated vesicles in acrosome formation.},
  author={Gareth Griffiths and Graham Warren and I Stuhlfauth and Brigitte M. Jockusch},
  journal={European journal of cell biology},
  volume={26 1},
Ultrastructural and cytochemical observations are presented which suggest that coated vesicles originating from the trans (distal) aspect of the rat spermatid Golgi apparatus transport lysosomal enzymes from the Golgi to the developing acrosome. Using an affinity purified antibody against the clathrin coats of pig brain coated vesicles, immunofluorescence and immuno-electron microscopic studies were carried out on frozen sections of rat seminiferous tubules. The results showed a specific… CONTINUE READING

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