The role of chemotherapy and/or octreotide in patients with metastatic gastroenteropancreatic and hepatobiliary neuroendocrine carcinoma.

@article{Lee2014TheRO,
  title={The role of chemotherapy and/or octreotide in patients with metastatic gastroenteropancreatic and hepatobiliary neuroendocrine carcinoma.},
  author={Suk-Young Lee and Yoon Ji Choi and Won Jin Chang and Sang Won Shin and Yeul Hong Kim and Seung Tae Kim},
  journal={Journal of gastrointestinal oncology},
  year={2014},
  volume={5 6},
  pages={457-62}
}
BACKGROUND Neuroendocrine carcinomas (NECs) of the gastro-entero-pancreatic (GEP) and hepatobiliary (HB) tract are rare and a heterogenous group of malignancies. Octreotide showed the anti-tumor activity in functional and nonfunctional well differentiated metastatic midgut neuroendocrine tumors (NETs). However, the effect of octreotide on survival has not been evaluated. PATIENTS AND METHODS We analyzed 17 patients (6 HB- and 11 GEP- tract) with metastatic NEC diagnosed between January 2009… CONTINUE READING

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Octreotide showed the anti - tumor activity in functional and nonfunctional well differentiated metastatic midgut neuroendocrine tumors ( NETs ) .
Octreotide showed the anti - tumor activity in functional and nonfunctional well differentiated metastatic midgut neuroendocrine tumors ( NETs ) .
In univariate analysis , any clinico - pathologic features including sex , the location of primary tumor , the number of metastatic sites , the debulking operation and the liver metastasis did not have prognostic value regarding OS .
Octreotide showed the anti - tumor activity in functional and nonfunctional well differentiated metastatic midgut neuroendocrine tumors ( NETs ) .
Octreotide showed the anti - tumor activity in functional and nonfunctional well differentiated metastatic midgut neuroendocrine tumors ( NETs ) .
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