The role of charged multivesicular body protein 5 in programmed cell death in leukemic cells.


The Homo sapiens charged multivesicular body protein 5 (CHMP5) is a member of the multivesicular body, which serves as an anti-apoptotic protein and is thought to participate in leukemogenesis. In this study, a short-hairpin RNA-based RNA interference approach was used to inhibit the expression of CHMP5 in the leukemic cell line U937. After CHMP5 was… (More)
DOI: 10.1093/abbs/gmt028


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