The role of cellular motility in the invasion of human neuroblastoma cells with or without N-myc amplification and expression.

Abstract

BACKGROUND/PURPOSE Patients who have neuroblastomas with N-myc amplification that are extremely invasive and result in distant metastases tend to have a very poor prognosis. The authors reported previously that N-mycamplification and expression might be closely related to the invasiveness of human neuroblastoma cells. However, the role of cellular motility… (More)

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