The role of cell death in limb development of rats manifesting Lx allele on different genetic backgrounds.

@article{Sedmera1998TheRO,
  title={The role of cell death in limb development of rats manifesting Lx allele on different genetic backgrounds.},
  author={David Sedmera and Bo{\vz}ena Novotn{\'a} and Vlasta B{\'i}l{\'a} and Vladim{\'i}r Křen},
  journal={European journal of morphology},
  year={1998},
  volume={36 3},
  pages={
          173-81
        }
}
Control of vertebrate digital pattern is a phylogenetically old mechanism. Animal strains with abnormal digital counts are a useful model system to study tissue, cell and molecular factors involved in limb patterning. The aim of this study was to investigate rat limb morphogenesis on gestation days 13 to 16 in normodactylous, polydactylous and oligodactylous fetuses where the deviation from the normal pentadactylous phenotype is caused by interaction of mutant Lx allele with different genetic… CONTINUE READING