The role of cell adhesion molecules in cancer invasion and metastasis

@article{Behrens1993TheRO,
  title={The role of cell adhesion molecules in cancer invasion and metastasis},
  author={J{\"u}rgen Behrens},
  journal={Breast Cancer Research and Treatment},
  year={1993},
  volume={24},
  pages={175-184}
}
Invasion and metastasis of tumor cells is the primary cause for the fatal outcome of cancer diseases. A striking feature of metastatic cells is the considerable flexibility in their adhesive interactions with other cells or components of the extracellular matrix. This review will describe the involvement of specific cell adhesion receptors, extracellular matrix molecules, and cell dissociating cytokines in the metastatic cascade. We will particularly focus on disturbance of intercellular… CONTINUE READING