The role of cardiac autonomic function in hypertension and cardiovascular disease

@article{Palatini2009TheRO,
  title={The role of cardiac autonomic function in hypertension and cardiovascular disease},
  author={Paolo Palatini and Stevo Julius},
  journal={Current Hypertension Reports},
  year={2009},
  volume={11},
  pages={199-205}
}
Autonomic nervous system abnormality, clinically manifested as a hyperkinetic circulation characterized by elevations in heart rate, blood pressure, plasma norepinephrine levels, and cardiac output, has been repeatedly demonstrated in hypertension. Increased release of norepinephrine from the brain has also been described in hypertension, and increased sympathetic activity has been demonstrated using spectral analysis of heart rate variability, particularly in the early stage of hypertension… 

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Untreated hypertension does not disturb cardiovascular protective mechanisms during moderate cold exposure commonly occurring in everyday life, and blunt response of the estimate of peripheral sympathetic modulation may indicate higher tonic sympathetic activity and decreased sympathetic responsiveness to cold in hypertension.

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