The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats.

@article{Izzo1999TheRO,
  title={The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats.},
  author={Angelo A Izzo and Nicola Mascolo and Luisa Pinto and Raffaele Capasso and Francesco Capasso},
  journal={European journal of pharmacology},
  year={1999},
  volume={384 1},
  pages={37-42}
}
We have studied the effects of the cannabinoid receptor agonists (R)-(+)[2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2, 3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone (WIN 55,212-2, 0. 3-5 mg/kg, i.p.) and (-)-cis-3-[2-hydroxy-4-(1, 1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol) (CP 55,940, 0.03-1 mg/kg, i.p.), the cannabinoid CB(1) receptor antagonist (N-piperidin-1-yl)-5-(4-chlorophenyl)-1-2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A, 0. 3… CONTINUE READING