The role of brushite and octacalcium phosphate in apatite formation.

@article{Johnsson1992TheRO,
  title={The role of brushite and octacalcium phosphate in apatite formation.},
  author={Malena Johnsson and George H. Nancollas},
  journal={Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists},
  year={1992},
  volume={3 1-2},
  pages={61-82}
}
Studies of apatite mineral formation are complicated by the possibility of forming several calcium phosphate phases. The least soluble, hydroxyapatite (HAP), is preferentially formed under neutral or basic conditions. In more acidic solutions phases such as dicalcium phosphate dihydrate (Brushite, DCPD) and octacalcium phosphate (OCP) are often found. Even under ideal HAP precipitation conditions the precipitates are generally nonstoichiometric, suggesting the formation of calcium-deficient… CONTINUE READING

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