The role of brimonidine in the treatment of open-angle glaucoma.

  title={The role of brimonidine in the treatment of open-angle glaucoma.},
  author={Jacob T. Wilensky},
  journal={Survey of ophthalmology},
  volume={41 Suppl 1},
At present, medical therapy is the first line of attack against primary open-angle glaucoma. beta-blockers, miotics, sympathomimetics, carbonic anhydrase inhibitors, and prostaglandins have been used with varying degrees of success. The alpha 2-agonists, clonidine, apraclonidine, and now brimonidine are powerful inhibitors of aqueous humor production, thereby lowering intraocular pressure (IOP) in these patients. Brimonidine is emerging as a potential first-line therapy for primary open-angle… CONTINUE READING


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