The role of bone turnover markers in monitoring treatment in postmenopausal osteoporosis.

@article{Szulc2012TheRO,
  title={The role of bone turnover markers in monitoring treatment in postmenopausal osteoporosis.},
  author={P Szulc},
  journal={Clinical biochemistry},
  year={2012},
  volume={45 12},
  pages={907-19}
}
Bone metabolism is assessed using biochemical bone turnover markers (BTM). BTM reflect the metabolic effect of drugs on bone turnover, help to establish the lowest dose inducing the largest change in the BTM, predict treatment-related reduction in fracture risk, and are helpful in bridging studies. Changes in BTM during anti-osteoporotic therapy depend on the cellular mechanism of action of the drug, degree of change in bone turnover rate and route of administration. BTM help to establish the… CONTINUE READING

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