The role of bone morphogenetic proteins in articular cartilage development, homeostasis and repair.

@article{Oshin2007TheRO,
  title={The role of bone morphogenetic proteins in articular cartilage development, homeostasis and repair.},
  author={A O Oshin and Matthew C. Stewart},
  journal={Veterinary and comparative orthopaedics and traumatology : V.C.O.T},
  year={2007},
  volume={20 3},
  pages={151-8}
}
Bone morphogenetic proteins (BMPs) are members of the TGF-beta superfamily of secreted ligands. BMPs regulate a diverse range of developmental processes during embryogenesis and postnatal development, and control the differentiation of several musculoskeletal tissues including bone, cartilage, tendon and ligaments. The ability of BMPs to modulate the phenotype of cells in these tissue lineages suggests that these factors could be valuable for musculoskeletal tissue regeneration. In fact, BMPs-2… CONTINUE READING

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