The role of blood stem cells in hematopoietic cell renewal.

  title={The role of blood stem cells in hematopoietic cell renewal.},
  author={Theodor M. Fliedner},
  journal={Stem cells},
  volume={16 Suppl 1},
It has been the purpose of this keynote address to review available evidence for the notion that the stem and progenitor cells circulating in the peripheral blood play a decisive role in the homeostasis of blood cell formation distributed throughout dozens of bone marrow units in the skeleton. Furthermore, if this notion is correct, one could speculate that the quantity and quality of stem and progenitor cells in the blood should reflect the functional state of the hematopoietic stem cell… CONTINUE READING

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