The role of biological markers of epithelial to mesenchymal transition in oesophageal adenocarcinoma, an immunohistochemical study.

@article{Prins2015TheRO,
  title={The role of biological markers of epithelial to mesenchymal transition in oesophageal adenocarcinoma, an immunohistochemical study.},
  author={M. J. D. Prins and J. P. Ruurda and Martijn P J Lolkema and Robert Sitarz and F. J. W. ten Kate and Richard van Hillegersberg},
  journal={Journal of clinical pathology},
  year={2015},
  volume={68 7},
  pages={
          529-35
        }
}
BACKGROUND E-cadherin, β-catenin, epidermal growth factor receptor (EGFR), neuronal cadherin (N-cadherin) and Cyclin D1 are involved in epithelial to mesenchymal transition (EMT). However, the prognostic significance of EMT markers in oesophageal adenocarcinoma (OAC) is unknown. Aim of this study was to evaluate the prognostic value of, and the association between different EMT markers in OAC. METHODS Tumour cores of 154 patients with OAC were included in a tissue microarray. Scoring criteria… CONTINUE READING
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