The role of bevacizumab in the treatment of glioblastoma

@article{Diaz2017TheRO,
  title={The role of bevacizumab in the treatment of glioblastoma},
  author={Roberto Jose Diaz and Sheikh C. Ali and Mehreen Gull Qadir and Macarena de la Fuente and Michael E. Ivan and Ricardo J. Komotar},
  journal={Journal of Neuro-Oncology},
  year={2017},
  volume={133},
  pages={455-467}
}
Bevacizumab has been used in patients with GBM as a salvage therapy since its approval in the United States for recurrent GBM in 2009. In order to review the therapeutic effect of bevacizumab in the primary and recurrent clinical setting we have performed a systematic analysis of data from the published literature. Weighted median progression free survival and overall survival were calculated and compared to standard therapy or other experimental therapies. A qualitative analysis of the limited… 

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Abstract Background. Currently, bevacizumab (BEV), an antiangiogenic agent, is used as an adjunctive therapy to re-irradiation and surgery in patients with recurrent high-grade gliomas (rHGG). BEV
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