The role of beta-1-adrenoceptors in the renin release response to graded renal sympathetic nerve stimulation

@article{Kopp2004TheRO,
  title={The role of beta-1-adrenoceptors in the renin release response to graded renal sympathetic nerve stimulation},
  author={Ulla C. Kopp and Mattias Aurell and Inga Marie Nilsson and Bengt {\AA}blad},
  journal={Pfl{\"u}gers Archiv},
  year={2004},
  volume={387},
  pages={107-113}
}
The contribution of beta-adrenoceptor activation to renin release was examined in anaesthetized dogs using renal nerve stimulation (RNS) at different discharge rates in the presence of i.v. beta-adrenoceptor blockade. The animals were divided into 2 groups, which received either low or high level of RNS, defined by the frequency of stimulation producing decrease in renal blood flow of 5 and 50%, respectively. Low level RNS increased renin release tenfold. The renin release response was almost… Expand
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