The role of benzoyl peroxide in the management of acne vulgaris
@article{Tucker2007TheRO, title={The role of benzoyl peroxide in the management of acne vulgaris}, author={Rod Tucker and Shernaz Walton}, journal={The Pharmaceutical Journal}, year={2007}, volume={279}, pages={48-53} }
A cne vulgaris is an extremely common and distressing condition that affects over 90 per cent of adolescents between the age of 16 and 18 years. Of these, approximately 15 per cent require medical intervention. Furthermore, research has shown that acne has a negative impact on patients’ quality of life that is comparable to that caused by conditions such as asthma and epilepsy. Although predominately a teenage problem, acne can and does persist into adult life and still affects roughly 1 per…
No Paper Link Available
14 Citations
Rediscovering Topical Antimicrobial Therapy for Acne Vulgaris
- Medicine, Biology
- 2009
Rediscovering Topical Antimicrobial Therapy for Acne Vulgaris - rediscovering the benefits of various combination therapies for patients and, subsequently, better compliance.
An Assessment of the Efficacy and Safety of Dapsone Gel: Study in a Local Setting
- MedicineScholars Journal of Applied Medical Sciences
- 2021
Dapsone gel was found to be more effective than Clindamycin cream in the treatment of acne vulgaris, and this study demonstrated lower systemic exposure with daps one gel formulations than with Clind amycin cream.
Topical antimicrobial acne treatment tolerability: a meaningful factor in treatment adherence?
- MedicineJournal of the American Academy of Dermatology
- 2014
Tracing the evidence in support of claims that tolerability of acne treatments affects adherence
- Medicine
- 2014
dherence to dermatologic treatment is assessed across the remaining 34 studies of topical A estimated to range from 55% to 66% but is as low as 45% for daily application of topical antimicrobial acne…
Formulation and evaluation of a topical niosomal gel containing a combination of benzoyl peroxide and tretinoin for antiacne activity
- BiologyInternational journal of nanomedicine
- 2015
In vivo studies of the niosomal gel and antiacne cream of TRA and BPO showed that the nioomal gel was more efficacious than the anti-ac acne cream because niosome gels with a 4.16-fold lower dose of BPO provided the same therapeutic index at targeted sites in comparison to the antiacNE cream.
An aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for the once-daily treatment of moderate to severe acne vulgaris: assessment of efficacy and safety in 2813 patients.
- MedicineJournal of the American Academy of Dermatology
- 2008
Acne management and patient support - a nursing concern for all.
- Medicine
- 2010
The principles of acne management are outlined, how nurses can support acne sufferers in their clinical practice is identified and how to prevent severe acne and scarring is identified.
A New, Once-daily, Optimized, Fixed Combination of Clindamycin Phosphate 1.2% and Low-concentration Benzoyl Peroxide 2.5% Gel for the Treatment of Moderate-to-Severe Acne.
- Chemistry, BiologyThe Journal of clinical and aesthetic dermatology
- 2009
Following a clinical program that studied more than 2,800 patients, clindamycin-benzoyl peroxide 2.5% was found to be highly effective and well tolerated and was recently introduced for the once-daily treatment of inflammatory and noninflammatory lesions in moderate-to-severe acne.
Prescribing for mild to moderate acne
- Medicine
- 2010
To achieve this, nurse prescribers need to understand the aetiology of acne and the four key stages that define acne as comedonal, mild, moderate and severe, as treatments need to be advised and prescribed according to severity and extent of the condition.
FORMULATION AND EVALUATION OF GEL CONTAINING ETHOSOMES ENTRAPPED WITH TRETINOIN
- BiologyJournal of Drug Delivery and Therapeutics
- 2018
It is suggested that the ethosomes are an efficient carrier for dermal and transdermal delivery of tretinoin and has smaller vesicular size than the liposomes prepared without alcohol.
References
SHOWING 1-10 OF 94 REFERENCES
Treatment of acne vulgaris with salicylic acid pads.
- MedicineClinical therapeutics
- 1992
Comparative studies of salicylic acid have shown it to be superior to benzoyl peroxide in reducing the total number of acne lesions and to be comparable to conventional antibiotics in preventing and treating acne vulgaris.
A COMPARATIVE STUDY OF GLUCONOLACTONE VERSUS BENZOYL PEROXIDE IN THE TREATMENT OF ACNE
- MedicineThe Australasian journal of dermatology
- 1992
The results of this study showed that both gluconolactone and benzoyl peroxide had a significant effect in improving patients' acne by reducing the number of lesions (inflamed and non‐inflated).
Studies on the Mechanism of Action of Topical Benzoyl Peroxide and Vitamin A Acid in Acne Vulgaris
- Medicine, BiologyJournal of cutaneous pathology
- 1974
The effective agent, benzoyl peroxide, produced a mild desquamation: while concommitantly reducing the fatty acids in sebum more dramatically than systemic tetracycline.
Evolution of a strategy for the treatment of acne.
- MedicineJournal of the American Academy of Dermatology
- 1987
Benzoyl peroxide in seborrheic dermatitis.
- MedicineArchives of dermatology
- 1986
The treatment of patients with seborrheic dermatitis of the face with benzoyl peroxide at a concentration of 2.5% in a base was strikingly effective in all but two patients.
Treatment of acne vulgaris.
- MedicineJAMA
- 2004
The best evidence available for individualized treatment of acne is reviewed to review, with a focus on randomized controlled trials, meta-analyses, and other systematic reviews.
Benzoyl peroxide versus topical erythromycin in the treatment of acne vulgaris.
- Medicine, BiologyThe British journal of dermatology
- 1983
The view is that, although topical erythromycin is of value in the treatment of mild or moderate acne vulgaris, long established, safe and effective remedies should not be replaced by topical antibiotics until more comparative studies and investigations on bacterial resistance have been completed.
Benzoylperoxide versus topical erythromycin in the treatment of acne vulgaris
- Medicine, Biology
- 1983
The view is that, although topical erythromycin is of value in the treatment of mild or moderate acne vulgaris, long established, safe and effective remedies should not be replaced by topical antibiotics until more comparative studies and investigations on bacterial resistance have been completed.
Local treatment of acne. A clinical study and evaluation of the effect of different concentrations of benzoyl peroxide gel.
- MedicineCurrent medical research and opinion
- 1981
A total of 50 patients with moderately severe acne was treated with either 3%, 5% or 10% benzoyl peroxide gel for 4 weeks and in all the remaining cases a definite remission of the acne activity could be observed at the end of the 4-weeks' trial.
Management of acne vulgaris.
- MedicineAmerican family physician
- 1994
Clinical manifestations of acne range from noninflammatory comedones to inflammatory papules, pustules and cysts, and current therapy allows the physician to select a variety of topical and/or systemic antibiotics, retinoids, and hormone agents aimed at specific pathogenic factors.