The role of bacterial proteases in the pathogenesis of cystic fibrosis.

  • Steve Suter
  • Published 1994 in
    American journal of respiratory and critical care…


Among the roles of mediators damaging the respiratory epithelium in patients with cystic fibrosis (CF) during the course of chronic, purulent bronchitis, that of neutrophil proteases is well established. The role of bacterial proteases is less well known. Among all pathogens colonizing the airways in CF, Pseudomonas aeruginosa is quantitatively the dominant… (More)


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