The role of apoptosis in autoantibody production.


Apoptosis is the physiologic process that guarantees the cellular exchange; after apoptosis the cellular remains are cleared by phagocytosis. In autoimmunity, some mechanisms in apoptosis fail and may result in disease. For instance, a failure in the Fas pathway during lymphoid ontogeny may allow the survival of autoimmune clones; equally the lack of… (More)


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@article{HerreraEsparza2007TheRO, title={The role of apoptosis in autoantibody production.}, author={Rafael Herrera-Esparza and D Herrera-van-Oostdam and Er{\'e}ndira L{\'o}pez-Robles and Esperanza Avalos-D{\'i}az}, journal={Reumatismo}, year={2007}, volume={59 2}, pages={87-99} }