The role of antioxidants in models of inflammation: Emphasis on l-arginine and arachidonic acid metabolism

@article{Kapoor2005TheRO,
  title={The role of antioxidants in models of inflammation: Emphasis on l-arginine and arachidonic acid metabolism},
  author={Mohit Kapoor and Andrew N. Clarkson and Brad Sutherland and Ian Appleton},
  journal={InflammoPharmacology},
  year={2005},
  volume={12},
  pages={505-519}
}
Inflammatory processes are made up of a multitude of complex cascades. Under physiological conditions these processes aid in tissue repair. However, under pathophysiological environments, such as wound healing and hypoxia-ischaemia (HI), inflammatory mediators become imbalanced, resulting in tissue destruction. This review addresses the changes in reactive oxygen species (ROS), l-arginine and arachidonic acid metabolism in wound healing and HI and subsequent treatments with promising anti… CONTINUE READING

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