The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener granulomatosis. A literature review and meta-analysis.

@article{Rao1995TheRO,
  title={The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener granulomatosis. A literature review and meta-analysis.},
  author={J. Koteswara Rao and Malvin Weinberger and Eugene Oddone and Nancy B Allen and Pavel Landsman and John R. Feussner},
  journal={Annals of internal medicine},
  year={1995},
  volume={123 12},
  pages={
          925-32
        }
}
Wegener granulomatosis is a serious systemic vasculitis that is uniformly fatal if untreated. In 1983, Fauci and colleagues [1] reported their success with a combination of corticosteroid and cyclophosphamide therapy in 85 patients with Wegener granulomatosis. Since then, the recognition among clinicians of Wegener granulomatosis and its expanded clinical spectrum has improved, making early diagnosis and treatment possible. Patients with the classic Wegener triad have necrotizing granulomatous… CONTINUE READING
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