The role of antigen form and function in the primary and secondary intestinal immune responses to cholera toxin and toxoid in rats

@article{Pierce1978TheRO,
  title={The role of antigen form and function in the primary and secondary intestinal immune responses to cholera toxin and toxoid in rats},
  author={N X Pierce},
  journal={The Journal of Experimental Medicine},
  year={1978},
  volume={148},
  pages={195 - 206}
}
  • N X Pierce
  • Published 1978 in The Journal of experimental medicine
This report describes studies of the mucosal antitoxic response in rats after enteric administration of several forms of cholera toxin or toxoid, proteins which differ primarily in their ability to bind to cell membranes and activate cellular adenyl cyclase. These two characteristics appeared to markedly enhance the local primary response to these antigens… CONTINUE READING