The role of antibodies to PrP in the diagnosis of transmissible spongiform encephalopathies.

@article{Kascsak1993TheRO,
  title={The role of antibodies to PrP in the diagnosis of transmissible spongiform encephalopathies.},
  author={Richard J. Kascsak and M S Tonna-DeMasi and R Fersko and Richard Rubenstein and Richard I. Carp and J Michael Powers},
  journal={Developments in biological standardization},
  year={1993},
  volume={80},
  pages={141-51}
}
Transmissible spongiform encephalopathies (TSE) are progressive degenerative disorders of the central nervous system. Efficient and accurate identification of these disorders is necessitated by their transmissibility and fatal prognosis. The availability of polyclonal and monoclonal antibodies to a TSE disease-specific protein marker PrPSC affords the… CONTINUE READING