The role of antiandrogen monotherapy in the treatment of prostate cancer

@article{Anderson2003TheRO,
  title={The role of antiandrogen monotherapy in the treatment of prostate cancer},
  author={J. B. Anderson},
  journal={BJU International},
  year={2003},
  volume={91}
}
  • J. Anderson
  • Published 26 February 2003
  • Medicine, Biology
  • BJU International
The mainstay of hormonal therapy in prostate cancer has been medical or surgical castration, both of which are associated with loss of libido and impotence, and may not always be acceptable to the patient. Antiandrogen monotherapy is an alternative treatment option to castration. There are two types of antiandrogen, i.e. steroidal (cyproterone acetate, CPA), and nonsteroidal (bicalutamide, flutamide and nilutamide). Data comparing survival outcome with CPA and castration are limited and… 

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References

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As the primary hormonal therapy for stage D2 prostate cancer, DES caused more serious cardiovascular or thromboembolic complications than flutamide, andFlutamide was not as active an initial agent as DES, however, the effectiveness of flutamia in conjunction with other agents compared with DES remains undetermined.