The role of angiopoietins during angiogenesis in gliomas.

  title={The role of angiopoietins during angiogenesis in gliomas.},
  author={Yvonne Reiss and M{\'a}rcia Regina Machein and Karl Heinz Plate},
  journal={Brain pathology},
  volume={15 4},
The formation of new blood vessels plays an important role in human disease development and progression. For instance, it is well established that the growth of most cancers critically depends on the supply of nutrition and oxygen by newly recruited blood vessels. Similarly, malignant gliomas, the most common primary brain tumors occurring in humans are highly dependent on angiogenesis. In recent years, there has been tremendous effort to uncover the molecular mechanisms that drive blood vessel… CONTINUE READING