The role of airflow resistance in patients with the adult respiratory distress syndrome.

@article{Wright1989TheRO,
  title={The role of airflow resistance in patients with the adult respiratory distress syndrome.},
  author={Paul E. Wright and Gordon R. Bernard},
  journal={The American review of respiratory disease},
  year={1989},
  volume={139 5},
  pages={1169-74}
}
Although reduced lung compliance is a hallmark of the adult respiratory distress syndrome (ARDS), the role of increased airflow resistance in this disorder has not been well studied. Because animal models of ARDS show marked increases in airflow resistance and because mediators known to participate in lung parenchymal injury have also been implicated in models of increased airway reactivity, we hypothesized that increased airflow resistance is a major contributor to altered lung mechanics in… CONTINUE READING

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