The role of agouti-related protein in regulating body weight.

Abstract

Defects in signaling by leptin, a hormone produced primarily by adipose tissue that informs the brain of the body's energy reserves, result in obesity in mice and humans. However, the majority of obese humans do not have abnormalities in leptin or its receptor but instead exhibit leptin resistance that could result from defects in downstream mediators of… (More)

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@article{Wilson1999TheRO, title={The role of agouti-related protein in regulating body weight.}, author={Bradley D Wilson and Mike Ollmann and Gregory S Barsh}, journal={Molecular medicine today}, year={1999}, volume={5 6}, pages={250-6} }