The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance.

@article{Goossens2008TheRO,
  title={The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance.},
  author={Gijs H Goossens},
  journal={Physiology & behavior},
  year={2008},
  volume={94 2},
  pages={206-18}
}
Research of the past decade has increased our understanding of the role adipose tissue plays in health and disease. Adipose tissue is now recognized as a highly active metabolic and endocrine organ. Adipocytes are of importance in buffering the daily influx of dietary fat and exert autocrine, paracrine and/or endocrine effects by secreting a variety of adipokines. The normal function of adipose tissue is disturbed in obesity, and there is accumulating evidence to suggest that adipose tissue… CONTINUE READING