The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints

@inproceedings{Lee2014TheRO,
  title={The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints},
  author={Yeon-Ah Lee and H Ji and Sang-Hoon Lee and Seung-Jae Hong and Hyung In Yang and Myung Chul Yoo and Kyoung Soo Kim},
  booktitle={Experimental & Molecular Medicine},
  year={2014}
}
This study was performed to evaluate the contribution of adiponectin to the production of interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-1 and MMP-13 in human endothelial cells and osteoblasts in arthritic joints. Cultured human umbilical vascular endothelial cells (HUVECs) and osteoblasts were stimulated with adiponectin (1 or 10 μg ml−1) or IL-1β (0.1 ng ml−1) in the presence or absence of hypoxia for 24 h. The protein expression patterns… CONTINUE READING
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