The role of acquisition and quantification methods in myocardial blood flow estimability for myocardial perfusion imaging CT.

@article{Eck2018TheRO,
  title={The role of acquisition and quantification methods in myocardial blood flow estimability for myocardial perfusion imaging CT.},
  author={Brendan L. Eck and Raymond F. Muzic and Jacob Levi and Hao Wu and Rachid Fahmi and Yuemeng Li and Anas Fares and Mani Vembar and Amar Dhanantwari and Hiram G. Bezerra and David L. Wilson},
  journal={Physics in medicine and biology},
  year={2018},
  volume={63 18},
  pages={
          185011
        }
}
In this work, we clarified the role of acquisition parameters and quantification methods in myocardial blood flow (MBF) estimability for myocardial perfusion imaging using CT (MPI-CT). We used a physiologic model with a CT simulator to generate time-attenuation curves across a range of imaging conditions, i.e. tube current-time product, imaging duration, and temporal sampling, and physiologic conditions, i.e. MBF and arterial input function width. We assessed MBF estimability by precision… CONTINUE READING
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