The role of a repetitive palindromic sequence element in the human cytomegalovirus major immediate early enhancer.

@article{Fickenscher1989TheRO,
  title={The role of a repetitive palindromic sequence element in the human cytomegalovirus major immediate early enhancer.},
  author={Helmut Fickenscher and Thomas Stamminger and Ruediger Rueger and Bernhard Fleckenstein},
  journal={The Journal of general virology},
  year={1989},
  volume={70 ( Pt 1)},
  pages={107-23}
}
The major enhancer, extending from nucleotides -530 to -120 upstream of the transcription initiation site of immediate early (IE) genes 1 and 2 in human cytomegalovirus (HCMV), contains four groups of repeated sequence motifs that consist of 17, 18, 19 or 21 bp, respectively. One of these elements, the 19 bp repeat, is a symmetrical palindrome that is also part of IE regulatory sequences of other cytomegalovirus-type herpesviruses, but not of unrelated members of the herpesvirus group… CONTINUE READING
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