The role of WT1 gene in neuroblastoma.

Abstract

BACKGROUND/PURPOSE The oncogenic properties of the Wilms' tumor gene (WT1) have recently been reported in various malignancies. However, the role of WT1 in pediatric tumors is unclear. To elucidate the role of WT1 in the development of neuroblastoma (NB), we examined the WT1 expression in NB and the effect of WT1 suppression on NB cell proliferation… (More)
DOI: 10.1016/j.jpedsurg.2010.11.011

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