The role of VEGF and thrombospondins in skin angiogenesis.

  title={The role of VEGF and thrombospondins in skin angiogenesis.},
  author={Michael Detmar},
  journal={Journal of dermatological science},
  volume={24 Suppl 1},
The vasculature in adult skin remains normally quiescent, due to the dominant influence of endogenous angiogenesis inhibitors over angiogenic stimuli. However, skin retains the capacity for brisk initiation of angiogenesis, the growth of new blood vessels from preexisting vessels, during tissue repair and in numerous diseases, including inflammatory skin diseases such as psoriasis and skin cancers such as cutaneous squamous cell carcinomas. Moreover, cyclic vascular expansion occurs during the… CONTINUE READING
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