The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats.

@article{Trkdoan2003TheRO,
  title={The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats.},
  author={M K{\"u}rşad T{\"u}rkdoğan and Hanefi Ozbek and Zabit Yener and Ilhan Tuncer and Ismail Uygan and Emel Mashaki Ceylan},
  journal={Phytotherapy research : PTR},
  year={2003},
  volume={17 8},
  pages={942-6}
}
The role of Nigella sativa L. (Ranunculaceae) (NS) and Urtica dioica L. was investigated (UD) in the prevention of carbon tetrachloride (CCl4) induced liver fibrosis and cirrhosis. Fifty Sprague-Dawley rats were allocated into fi ve groups (I, IIA and B, IIIA and B) and CCl4 was injected biweekly to all groups. Group I (control, CCl4 only), group IIA and B (NS fixed oil and volatile oil), group IIIA and B (UD fixed oil and UD decoction extract) rats were killed at the end of week 12 and… CONTINUE READING
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